Adipeau maintains an active program of observational cohorts and clinical studies. Studies listed below are declared prospectively — before completion of follow-up — to document our evidence pipeline with full transparency. Where externally registered, the registry link is provided.
Studies Pipeline
RCT-3
Skin Laxity Study
Registered
Ongoing
| Population | Product | Follow-up | N | Registry |
|---|---|---|---|---|
| Women aged 45–75 with overt skin laxity on legs | Strength Gel | 3 months | Enrolling (target: 30) | ISRCTN11066382 |
Details
| Purpose | To evaluate contour uniformity changes in subjects older than 45 with overt skin laxity on legs |
| Primary endpoint | Change in laxity severity measured using the Merz Laxity Scale at baseline and 3 months |
| Measurement | Blinded evaluators applying Merz Laxity Scale |
| Follow-up started | 13 February 2026 |
| Expected completion | 14 October 2026 |
| Listed on this page | 13 April 2026 |
GLP1C-1
Post GLP-1 Weight Loss Cohort
Ongoing
| Population | Product | Follow-up | N |
|---|---|---|---|
| Individuals with prior GLP-1–associated weight loss, weight stabilized, with visible skin changes | Strength Gel | 3 and 6 months | Enrolling (target: 30) |
Details
| Purpose | To evaluate contour uniformity changes in subjects using GLP-1 medications during a period of Adipeau use |
| Primary endpoint | Contour uniformity of face as manifested by vertical contour balance and horizontal contour continuity |
| Measurement | In-clinic imaging and blinded evaluation. |
| Recruitment | Partner clinics and targeted outreach |
| Follow-up started | 30 March 2026 |
| Expected completion | 30 October 2026 |
| Registry | Not externally registered. Declared on this page prior to completion of follow-up. |
| Listed on this page | 13 April 2026 |
POSC-1
PROVOKED Older Skin Cohort
Ongoing
| Population | Product | Follow-up | N |
|---|---|---|---|
| Women aged 40+ from the PROVOKED community | Both | 3 months | Enrolled: 14 |
Details
| Purpose | To evaluate contour uniformity changes in subjects aged 50+ working for PROVOKED magazine |
| Primary endpoint | Contour uniformity of face as manifested by vertical contour balance and horizontal contour continuity |
| Measurement | Self-submitted photography, blinded evaluators |
| Follow-up started | 2 April 2026 |
| Expected completion | 2 August 2026 |
| Registry | Not externally registered. Declared on this page prior to completion of follow-up. |
| Listed on this page | 13 April 2026 |
BSEC-1
Breast Skin Exploratory Cohort
Ongoing
| Population | Product | Follow-up | N |
|---|---|---|---|
| Women aged 30+ seeking to improve breast skin strength | Strength Gel | 3 and 6 months | Enrolling (target: 15) |
Details
| Purpose | To explore changes in breast skin during a period of Adipeau use |
| Primary endpoint | Exploratory — changes in breast skin texture, shape, and firmness |
| Measurement | Self-submitted photography and self-evaluation |
| Follow-up started | 1 December 2025 |
| Expected completion | 1 August 2026 |
| Registry | Not externally registered. Declared on this page prior to completion of follow-up. |
| Listed on this page | 13 April 2026 |
NRC-1
Non-Responder Follow-Up Cohort
Ongoing
| Population | Product | Follow-up | N |
|---|---|---|---|
| Individuals using the product for 3+ months without desired outcomes | Both | 3 and 6 months | Enrolling (target: 15) |
Details
| Purpose | To evaluate whether subjects who reported dissatisfaction with prior Adipeau use show visible contour changes during a structured follow-up period |
| Primary endpoint | Contour uniformity of face as manifested by vertical contour balance and horizontal contour continuity |
| Measurement | Self-submitted photography, blinded evaluators |
| Follow-up started | 13 April 2026 |
| Expected completion | 13 October 2026 |
| Registry | Not externally registered. Declared on this page prior to completion of follow-up. |
| Listed on this page | 13 April 2026 |
Planned Pooled Analysis
Subjects from NRC-1, GLP1C-1, and POSC-1 will be pooled and evaluated by blinded observers.
PRIMARY
Whether blinded observers can correctly determine which image is before and which is after
SECONDARY
Whether contour uniformity — horizontal and vertical — is improved
Studies not registered on an external registry were declared on this page prior to completion of follow-up. Page listing dates are verifiable via archived snapshots. Target enrollment (N) is listed for ongoing studies; actual evaluable N will be reported upon completion.
