In this article:
- The Zombie reality pt1
- The Zombie scare pt2
- Do I have a zombie problem?
- Is there a zombie killer cream?
- The clinical studies: Rapamycin vs. OneSkin
- What if I have weak skin?
- Fat cell size explains why the skin sags
- Bloated fat cells suppress collagen and elastin production
- The Zombie scare
- The Strength Gel restores healthy fat cell size
- The Adipeau regimen restores strong skin
Part 1.
The Zombie reality
The scientific literature shows that the zombie problem is limited to one cell type – melanocytes – which increase at a linear, rather than exponential rate.
Part 2.
The Zombie reality
Zombie melanocytes cause a gradual buildup of discoloration in sun exposed areas.
Do I have a zombie problem?
Is there a zombie killer cream?
Yes. Topical rapamycin treats pigment dysfunction associated with zombie cells.
Fig. 3 Rapamycin treatment improves clinical signs of aging in the skin. Clinical improvement in a 65-year-old woman (a) and a 67-year-old woman (b) following application of 10 μM rapamycin cream for 6–8 months. The placebo-treated hand is provided for comparison. in c, overall clinical improvement on 3 scales, the Glogau Classification of Photoaging, wrinkling measured on a 1-4 Likert scale, and the Merz Hand Grading Scale for aging skin, is presented for all subjects completing the study. Lower score on all scales correlates with reduced clinical severity.
The clinical studies: Rapamycin vs. OneSkin.
Comparative Summary of Topical Rapamycin (GeroScience, 2019) and OS-01 Peptide (J Cosmet Dermatol, 2024).
| Criterion | Topical Rapamycin (GeroScience, 2019) | OS-01 Peptide (J Cosmet Dermatol, 2024) |
|---|---|---|
| 1. Protocol published in clinical trials repository | Yes – Registered on ClinicalTrials.gov(NCT03103893) | No evidence – No trial registration reported |
| 2. Registered protocol specifies primary / secondary endpoints | Yes – Primary: dermal thickness (6–8 mo); Secondary: gene expression, seborrheic keratosis severity | No – No pre-specified endpoints |
| 3. Publication reports on registered endpoints | Partially – Reports histology / gene expression but emphasizes exploratory outcomes (p16^INK4a, skin tone) | No – Reports only exploratory cosmetic outcomes (hydration, barrier, texture) |
| 4. Evaluates senescence markers | Yes – Reduced p16^INK4a; increased collagen VII | No – No senescence markers measured |
| 5. Evaluates pigmentation effects | Yes (qualitative) – Improved evenness / skin tone (not pre-specified or quantitative) | No – Pigmentation not assessed |
What if I have weak skin?
Mouth lines and eye hollows
are caused by insufficient fat cell regeneration.
Loose skin
is caused by bloated fat cells.
Saggy nasolabials and “jowling”
are caused by bloated fat cells.
Crepe-like skin
reflects insufficient elastin production.
Fat cell size explains why the skin sags.
Bloated fat cells suppress collagen and elastin production.
The Strength Gel restores healthy fat cell size.
The Adipeau regimen restores strong skin.
